Kill Depression Before It Kills You

It is so unfortunate that I will begin this post with mentioning something that is bitter. Depression kills. It is sad that it does kill, but what is sadder is the fact despite it being curable, people die of it! However much you feel like you are never going to get out of that dark shadow, depression can be terminated. There are various approaches you can kill depression before it kills you. It all depends on which one works for you best. Below are ways to help you deal with and cure depression.

How to deal with depression

Learn more about your depression

It is crucial to determine the cause of the depression first. Are the symptoms due to an underlying medical condition? Let it be treated first. Also, consider the severity of the condition so that you know the intensity of treatment you require.

Talk it out

Consider a person whom you can confide with. One who can pull you up instead of pressing you down. Don’t keep this negative energy all housed in your little soul, share your frustrations with somebody who can listen up. If possible, talk professionals such as therapists, psychologists, and doctors. They are better placed to advise on the treatment options right for you—whether medications, counseling, therapies or lifestyle changes. This way, you won’t feel like the whole burden is on your shoulders alone. Avoid a friend who brushes it off with “it will just pass” statement without being with you as it passes. Avoid the one who tells you your problem is just a shred of theirs.

Distract yourself from the norm

Routines can be boring and monotonous. They can be worse when one is depressed. To break out of such a condition, why can’t you take a tour to some place you have always admired? Visit the beach. Soak it your feet in the sand and let it tickle your toes. Watch the sunrise and sun set at the sea shore. Look at how the golden rays are reflected on the blue waters and get soaked in that relaxing and refreshing feeling. With a sigh of relief, exclaim at how God has blessed you to be alive. Indulge and immerse yourself in the beauty of a park nearby. Watch, listen, touch and smell nature in the park. These walks act as distractions to your condition, and with time you will end up appreciating every single aspect of life, hence avoiding too many worries and thinking about your condition.

Be open to little experimentation and change

You might not land on the best treatment at first. You may start with an antidepressant, and as it times goes by, you notice that enough exercise is all you need to beat depression. You may otherwise opt for therapy sessions, whereby looking for the best therapists may take some time. This, therefore, requires you to be open-minded as you approach the issue. Otherwise, disappointments might set in if the treatments you try at first do not work as you expect.

Adopt lifestyle changes

Eat healthily. Have good and enough sleep. Exercise regularly. And above all, love life. You can kill depression before it kills you. It is something you can do. It is something that anyone who loves themselves can do. Love yourself and don’t let depression kill you. Kill it first!





Is There Hope in Gene Therapy For Cure Of Hemophilia B?

Could this be good news for hemophilia B patients? Preliminary research shows that one dose of gene therapy can help hemophilia B patients. As described by the National Hemophilia Foundation, this is a hereditary disorder where a person lacks the protein required for blood clotting. It is also known as Christmas disease. Lack of a protein known as factor IX or productive of defective of the same is what results to hemophilia B. A hemophiliac person has a moderate or severe bleeding with a clotting factor level below or equal to 2% of levels in a healthy person.

Blood clotting

Normally, bleeding stops as a result of the coagulation cascade. Blood platelets gather together on the wound site, and then blood clotting factors work together to form a more permanent plug in the wounded area. Therefore, if one has a low amount of factor IX, clotting will not occur immediately, and so bleeding takes long to stop. According to the Foundation, Hemophilia B occurs once in every 5000 births. It can lead to excessive bleeding. People with the condition bleed very easily, and their blood takes long to clot. They are prone to experiencing spontaneous internal bleeding and painful swollen joint as a result of bleeding in the joints. This spontaneous bleeding may result to blood in stool and urine, deep bruises, bleeding gum, tight and painful joints, frequent nosebleeds and irritability in children. Symptoms that may constitute a medical emergency are such as vomiting repeatedly, severe headache, double or blurred vision, neck pain, extreme sleepiness and continuous bleeding from an injury.

Gene therapy

With this new trial of gene therapy, researchers reported that there is no medical treatment which has ever boosted factor IX level to the same amount as gene therapy. According to the study, patients who had the gene therapy done on them were able to say goodbye to infusions of the clotting factor. The goal of the research was to increase gene therapy product safety and determine whether they could reach certain amounts of factor IX that could lower bleeding events. The objective is to edit a defective gene to attain a complete reversion of a disease phenotype for the lifetime of a patient. In the current treatment, in a week a patient gets a couple of intravenous doses of factor IX, and still, these levels fluctuate. According to the research, with one dose of gene therapy patients’ factor IX levels went up to around 30, which is almost normal! With these new levels, patients do not necessarily require to self-treat with factor IX to prevent bleeding events. This translates to a potential improvement in the quality of life plus a change in the way they view hemophilia treatment.